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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628662
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh1a3
Name: aldehyde dehydrogenase 1 family, member A3
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh1a3decreases expressionISOALDH1A3 (Homo sapiens)6480464CTDGlyphosate results in decreased expression of ALDH1A3 mRNAPMID:28711546
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