Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620944
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp7
Name: caspase 7
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp7multiple interactionsEXP 6480464CTD[Surface-Active Agents co-treated with Glyphosate] results in increased activity of CASP7 proteinPMID:23099315
Casp7increases activityISOCASP7 (Homo sapiens)6480464CTDGlyphosate results in increased activity of CASP7 proteinPMID:19105591
Casp7increases expressionISOCASP7 (Homo sapiens)6480464CTDGlyphosate results in increased expression of CASP7 mRNAPMID:31874349
Casp7multiple interactionsISOCASP7 (Homo sapiens)6480464CTD[Glyphosate co-treated with Herbicides] results in increased activity of CASP7 proteinPMID:19539684
Go Back to source page   Continue to Ontology report