Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3651
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cxcl12
Name: C-X-C motif chemokine ligand 12
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcl12decreases expressionISOCXCL12 (Homo sapiens)6480464CTDGlyphosate results in decreased expression of CXCL12 mRNAPMID:17984146
Cxcl12increases expressionISOCXCL12 (Homo sapiens)6480464CTDGlyphosate results in increased expression of CXCL12 mRNAPMID:28711546
Cxcl12multiple interactionsISOCXCL12 (Homo sapiens)6480464CTDGlyphosate promotes the reaction [Estradiol results in decreased expression of CXCL12 mRNA]PMID:17984146
Go Back to source page   Continue to Ontology report