Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2232
Species: Rattus norvegicus
RGD Object: Gene
Symbol: C3
Name: complement C3
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
C3decreases expressionEXP 6480464CTDGlyphosate results in decreased expression of C3 mRNAPMID:27463640 PMID:34850229
C3increases expressionISOC3 (Mus musculus)6480464CTDGlyphosate results in increased expression of C3 mRNA; Glyphosate results in increased expression of C3 proteinPMID:36608876
Go Back to source page   Continue to Ontology report