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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318458
Species: Homo sapiens
RGD Object: Gene
Symbol: SUSD2
Name: sushi domain containing 2
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SUSD2increases expressionISOSusd2 (Mus musculus)6480464CTDGlyphosate results in increased expression of SUSD2 mRNAPMID:35897073
SUSD2multiple interactionsISOSusd2 (Rattus norvegicus)6480464CTD[azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SUSD2 mRNAPMID:33854195
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