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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1315485
Species: Homo sapiens
RGD Object: Gene
Symbol: ATP8B4
Name: ATPase phospholipid transporting 8B4 (putative)
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ATP8B4decreases methylationISOAtp8b4 (Rattus norvegicus)6480464CTDGlyphosate results in decreased methylation of ATP8B4 genePMID:31011160
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