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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314330
Species: Homo sapiens
RGD Object: Gene
Symbol: BMP5
Name: bone morphogenetic protein 5
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BMP5decreases expressionEXP 6480464CTDGlyphosate results in decreased expression of BMP5 mRNAPMID:31295307
BMP5affects methylationISOBmp5 (Rattus norvegicus)6480464CTDGlyphosate affects the methylation of BMP5 genePMID:35440735
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