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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309080
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gadd45b
Name: growth arrest and DNA-damage-inducible, beta
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gadd45bincreases expressionISOGADD45B (Homo sapiens)6480464CTDGlyphosate results in increased expression of GADD45B mRNAPMID:31295307
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