Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308157
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cul1
Name: cullin 1
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cul1decreases expressionISOCUL1 (Homo sapiens)6480464CTDGlyphosate results in decreased expression of CUL1 mRNAPMID:31295307
Cul1decreases expressionISOCul1 (Mus musculus)6480464CTDGlyphosate results in decreased expression of CUL1 proteinPMID:37208198
Go Back to source page   Continue to Ontology report