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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620259
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eif4ebp1
Name: eukaryotic translation initiation factor 4E binding protein 1
Acc ID: CHEBI:27732
Term: caffeine
Definition: A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee.
Chemical ID: MESH:D002110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif4ebp1decreases expressionEXP 6480464CTDCaffeine results in decreased expression of EIF4EBP1 protein modified formPMID:21081844
Eif4ebp1increases expressionEXP 6480464CTDCaffeine results in increased expression of EIF4EBP1 proteinPMID:21081844
Eif4ebp1decreases expressionISOEIF4EBP1 (Homo sapiens)6480464CTDCaffeine results in decreased expression of EIF4EBP1 protein modified formPMID:21081844
Eif4ebp1decreases phosphorylationISOEIF4EBP1 (Homo sapiens)6480464CTDCaffeine results in decreased phosphorylation of EIF4EBP1 proteinPMID:35688186
Eif4ebp1increases expressionISOEIF4EBP1 (Homo sapiens)6480464CTDCaffeine results in increased expression of EIF4EBP1 proteinPMID:21081844
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