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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1606587
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP19A1
Name: cytochrome P450 family 19 subfamily A member 1
Acc ID: CHEBI:27732
Term: caffeine
Definition: A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee.
Chemical ID: MESH:D002110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP19A1increases expressionISOCyp19a1 (Rattus norvegicus)6480464CTDCaffeine results in increased expression of CYP19A1 mRNA; Caffeine results in increased expression of CYP19A1 proteinPMID:28111094
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