Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1563860
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rps6ka3
Name: ribosomal protein S6 kinase A3
Acc ID: CHEBI:27732
Term: caffeine
Definition: A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee.
Chemical ID: MESH:D002110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rps6ka3affects phosphorylationISORPS6KA3 (Homo sapiens)6480464CTDCaffeine affects the phosphorylation of RPS6KA3 proteinPMID:35688186
Rps6ka3decreases expressionISORPS6KA3 (Homo sapiens)6480464CTDCaffeine results in decreased expression of RPS6KA3 mRNAPMID:11793227
Go Back to source page   Continue to Ontology report