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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Clstn1
Name: calsyntenin 1
Acc ID: CHEBI:27732
Term: caffeine
Definition: A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee.
Chemical ID: MESH:D002110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Clstn1multiple interactionsISORGD:13150886480464CTD[Caffeine co-treated with 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine] results in decreased expression of CLSTN1 mRNA, Caffeine inhibits the reaction [1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine results in decreased expression of CLSTN1 mRNA]

PMID:20230807
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.