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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344163
Species: Homo sapiens
RGD Object: Gene
Symbol: NR1I3
Name: nuclear receptor subfamily 1 group I member 3
Acc ID: CHEBI:27727
Term: androstane-3,17-diol
Definition: A 17-hydroxy steroid that has formula C19H32O2.
Chemical ID: MESH:D015113
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR1I3multiple interactionsISONr1i3 (Mus musculus)6480464CTD1,4-bis(2-(3,5-dichloropyridyloxy))benzene inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein; arsenite inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; bisphenol A inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; butyl phosphorotrithioate inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; Chlorpyrifos inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; Corticosterone inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; cypermethrin inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; Diethylhexyl Phthalate inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; enilconazole inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; Methoxychlor inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; nonylphenol inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; Parathion inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]PMID:18832183
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