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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10869
Species: Mus musculus
RGD Object: Gene
Symbol: Lhb
Name: luteinizing hormone beta
Acc ID: CHEBI:27727
Term: androstane-3,17-diol
Definition: A 17-hydroxy steroid that has formula C19H32O2.
Chemical ID: MESH:D015113
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lhbincreases chemical synthesisISOLhb (Rattus norvegicus)6480464CTDLHB protein results in increased chemical synthesis of Androstane-3,17-diolPMID:31184881
Lhbincreases secretionISOLhb (Rattus norvegicus)6480464CTDLHB protein results in increased secretion of Androstane-3,17-diolPMID:24451217
Lhbmultiple interactionsISOLhb (Rattus norvegicus)6480464CTD2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [LHB protein results in increased secretion of Androstane-3,17-diol]; Flurbiprofen inhibits the reaction [LHB protein results in increased chemical synthesis of Androstane-3,17-diol]PMID:24451217 PMID:31184881
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