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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735269
Species: Homo sapiens
RGD Object: Gene
Symbol: DIO1
Name: iodothyronine deiodinase 1
Acc ID: CHEBI:27701
Term: oxytetracycline
Definition: A tetracycline used for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae (respiratory infections), and Diplococcus pneumoniae.
Chemical ID: MESH:D010118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DIO1decreases activityEXP 6480464CTDOxytetracycline results in decreased activity of DIO1 proteinPMID:29228274
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