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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69051
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgfb1
Name: transforming growth factor, beta 1
Acc ID: CHEBI:27684
Term: phenylmercury acetate
Definition: An arylmercury compound that has formula C8H8HgO2.
Chemical ID: MESH:D010662
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfb1decreases activityISOTGFB1 (Homo sapiens)6480464CTDPhenylmercuric Acetate results in decreased activity of TGFB1 proteinPMID:31652400
Tgfb1multiple interactionsISOTGFB1 (Homo sapiens)6480464CTDPhenylmercuric Acetate inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]PMID:31652400
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