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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307751
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srebf2
Name: sterol regulatory element binding transcription factor 2
Acc ID: CHEBI:27673
Term: herbacetin
Definition: A pentahydroxyflavone that is kaempferol substituted by a hydroxy group at position 8. It is a natural flavonoid from flaxseed which exerts antioxidant, anti-inflammatory and anticancer activities.
Chemical ID: MESH:C581534
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srebf2multiple interactionsISORGD:7309736480464CTDherbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF2 mRNA]

PMID:29653099
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.