GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bcl2 | decreases expression | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | Dactinomycin results in decreased expression of BCL2 mRNA; Dactinomycin results in decreased expression of BCL2 protein | PMID:12927789 PMID:17581298 | Bcl2 | multiple interactions | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | BCL2 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; Dactinomycin inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2 protein]; Dactinomycin inhibits the reaction [IL1B results in increased expression of BCL2 protein]; Dactinomycin inhibits the reaction [Paclitaxel results in increased phosphorylation of BCL2 protein]; Dactinomycin inhibits the reaction [TNF results in increased expression of BCL2 protein]; Morphine inhibits the reaction [Dactinomycin results in decreased expression of BCL2 protein]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in decreased expression of BCL2 protein]] | PMID:11726273 PMID:11880364 PMID:12927789 PMID:16492401 PMID:34303041 | | ||||||||||||||||||||||
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