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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620349
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:27647
Term: prostaglandin G2
Definition: A prostaglandins G that has formula C20H32O6.
Chemical ID: MESH:C038291
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2increases abundanceISOPtgs2 (Mus musculus)6480464CTDPTGS2 protein results in increased abundance of prostaglandin G2PMID:12538810
Ptgs2multiple interactionsISOPtgs2 (Mus musculus)6480464CTD[PTGS2 protein results in increased abundance of prostaglandin G2] inhibits the reaction [Sodium Salicylate inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]]; [PTGS2 protein results in increased abundance of prostaglandin G2] inhibits the reaction [Sodium Salicylate results in decreased activity of PTGS2 protein]PMID:12538810
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