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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731002
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP3
Name: caspase 3
Acc ID: CHEBI:27638
Term: cobalt atom
Definition: A cobalt group element atom that has atomic number 27.
Chemical ID: MESH:D003035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP3increases activityEXP 6480464CTDCobalt analog results in increased activity of CASP3 proteinPMID:21501578 PMID:28024936
CASP3increases expressionEXP 6480464CTDCobalt results in increased expression of CASP3 mRNAPMID:26378417
CASP3multiple interactionsISOCasp3 (Rattus norvegicus)6480464CTD[Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased activity of CASP3 proteinPMID:20934443
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