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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359491
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pou5f1
Name: POU class 5 homeobox 1
Acc ID: CHEBI:27638
Term: cobalt atom
Definition: A cobalt group element atom that has atomic number 27.
Chemical ID: MESH:D003035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pou5f1multiple interactionsISOPOU5F1 (Homo sapiens)6480464CTDAscorbic Acid inhibits the reaction [Cobalt results in increased expression of POU5F1 protein]; Cobalt promotes the reaction [SUMO1 protein results in increased expression of POU5F1 protein]; Cobalt results in increased expression of and results in increased stability of POU5F1 protein; Cycloheximide promotes the reaction [Cobalt results in increased expression of POU5F1 protein]PMID:24497960
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