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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:27618
Term: chalcone
Definition: A member of the class of chalcones that is acetophenone in which one of the methyl hydrogens has been replaced by a benzylidene group.
Chemical ID: MESH:D002599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases cleavageISOCASP3 (Homo sapiens)6480464CTDChalcone results in increased cleavage of CASP3 proteinPMID:20620131
Casp3multiple interactionsISOCASP3 (Homo sapiens)6480464CTDMYC protein affects the susceptibility to [Chalcone results in increased cleavage of CASP3 protein]PMID:20620131
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