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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68371
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mtor
Name: mechanistic target of rapamycin kinase
Acc ID: CHEBI:27616
Term: psoralen
Definition: The simplest member of the class of psoralens that is 7H-furo[3,2-g]chromene having a keto group at position 7. It has been found in plants like Psoralea corylifolia and Ficus salicifolia.
Chemical ID: MESH:D005363
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mtordecreases expressionISOMTOR (Homo sapiens)6480464CTDFicusin results in decreased expression of MTOR proteinPMID:35597499
Mtormultiple interactionsISOMTOR (Homo sapiens)6480464CTD5-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)-2,4-imidazolidinedione inhibits the reaction [Ficusin results in decreased expression of MTOR protein]; [Imatinib Mesylate co-treated with Ficusin] results in decreased expression of MTOR proteinPMID:35597499
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