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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620784
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnfsf11
Name: TNF superfamily member 11
Acc ID: CHEBI:27607
Term: thymol
Definition: A phenol that is a natural monoterpene derivative of cymene.
Chemical ID: MESH:D013943
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfsf11multiple interactionsISORGD:15516556480464CTDThymol inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CAR2 mRNA], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of GAB2 mRNA], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MITF mRNA], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 mRNA], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MMP9 protein], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of MYC mRNA], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA], Thymol inhibits the reaction [TNFSF11 protein results in increased expression of TNFRSF11A mRNA]

PMID:30048646
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.