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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2626
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fos
Name: Fos proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:27607
Term: thymol
Definition: A phenol that is a natural monoterpene derivative of cymene.
Chemical ID: MESH:D013943
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fosmultiple interactionsISORGD:105966480464CTDThymol inhibits the reaction [Lipopolysaccharides results in increased expression of FOS mRNA] Thymol inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA] Thymol inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein] Thymol promotes the reaction [Lipopolysaccharides results in decreased expression of FOS protein]

PMID:30048646
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