GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TGFB1 | increases expression | ISO | Tgfb1 (Rattus norvegicus) | 6480464 | CTD | Aldosterone results in increased expression of TGFB1 mRNA | PMID:25204689 | TGFB1 | increases secretion | ISO | Tgfb1 (Rattus norvegicus) | 6480464 | CTD | Aldosterone results in increased secretion of TGFB1 protein | PMID:15130897 | TGFB1 | multiple interactions | ISO | Tgfb1 (Rattus norvegicus) | 6480464 | CTD | [Aldosterone co-treated with Glucose] results in increased secretion of TGFB1 protein; [Aldosterone co-treated with Sodium Chloride, Dietary] results in increased expression of TGFB1 mRNA; [Eplerenone co-treated with Enalapril] inhibits the reaction [[Aldosterone co-treated with Glucose] results in increased secretion of TGFB1 protein]; [Eplerenone co-treated with Enalapril] inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of TGFB1 mRNA]]; Aldosterone promotes the reaction [Glucose results in increased expression of TGFB1 mRNA]; Enalapril inhibits the reaction [[Aldosterone co-treated with Glucose] results in increased secretion of TGFB1 protein]; Enalapril inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of TGFB1 mRNA]]; Eplerenone inhibits the reaction [[Aldosterone co-treated with Glucose] results in increased secretion of TGFB1 protein]; Eplerenone inhibits the reaction [[Aldosterone co-treated with Sodium Chloride, Dietary] results in increased expression of TGFB1 mRNA]; Eplerenone inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of TGFB1 mRNA]]; Spironolactone inhibits the reaction [Aldosterone results in increased expression of TGFB1 mRNA]; Spironolactone inhibits the reaction [Aldosterone results in increased secretion of TGFB1 protein]; tempol inhibits the reaction [Aldosterone results in increased expression of TGFB1 mRNA] | PMID:15130897 PMID:18682491 PMID:25204689 PMID:27773435 | | ||||||||||||||||||||||
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