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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737468
Species: Homo sapiens
RGD Object: Gene
Symbol: HSD11B2
Name: hydroxysteroid 11-beta dehydrogenase 2
Acc ID: CHEBI:27568
Term: selenium atom
Definition: A chalcogen that has formula Se.
Chemical ID: MESH:D012643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSD11B2multiple interactionsEXP 6480464CTD[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 protein]PMID:35384129
HSD11B2multiple interactionsISOHsd11b2 (Rattus norvegicus)6480464CTD[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of HSD11B2 mRNA; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 protein]; [Sodium Selenite results in increased abundance of Selenium] which results in increased expression of HSD11B2 proteinPMID:11444866 PMID:35384129
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