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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62076
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptges
Name: prostaglandin E synthase
Acc ID: CHEBI:27568
Term: selenium atom
Definition: A chalcogen that has formula Se.
Chemical ID: MESH:D012643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgesincreases expressionISOPTGES (Homo sapiens)6480464CTDSelenium results in increased expression of PTGES mRNAPMID:19244175
Ptgesmultiple interactionsISOPtges (Mus musculus)6480464CTD[Selenium deficiency co-treated with parthenolide co-treated with Lipopolysaccharides] results in decreased expression of PTGES mRNA; [Selenium deficiency co-treated with parthenolide co-treated with Lipopolysaccharides] results in decreased expression of PTGES proteinPMID:21669866
Ptgesmultiple interactionsISOPTGES (Homo sapiens)6480464CTD[Selenium co-treated with Vitamin E] results in increased expression of PTGES mRNAPMID:19244175
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