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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353510
Species: Homo sapiens
RGD Object: Gene
Symbol: TERT
Name: telomerase reverse transcriptase
Acc ID: CHEBI:27568
Term: selenium atom
Definition: A chalcogen that has formula Se.
Chemical ID: MESH:D012643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TERTdecreases activityEXP 6480464CTDSelenium results in decreased activity of TERT proteinPMID:17948765
TERTdecreases expressionEXP 6480464CTDSelenium results in decreased expression of TERT mRNAPMID:17948765
TERTmultiple interactionsISOTert (Rattus norvegicus)6480464CTDSelenium inhibits the reaction [Cadmium Chloride results in increased expression of TERT mRNA]PMID:16600092
TERTmultiple interactionsISOTert (Mus musculus)6480464CTD[Benzene co-treated with Selenium] results in increased activity of TERT proteinPMID:19080380
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