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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620979
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dnmt1
Name: DNA methyltransferase 1
Acc ID: CHEBI:27566
Term: 6-prenylnaringenin
Definition: A trihydroxyflavanone having a structure of naringenin prenylated at C-6.
Chemical ID: MESH:C521871
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dnmt1multiple interactionsISORGD:13541786480464CTD6-prenylnaringenin inhibits the reaction [DNMT1 protein binds to CYP1A1 promoter] 6-prenylnaringenin inhibits the reaction [Estradiol promotes the reaction [DNMT1 protein binds to CYP1A1 promoter]]

PMID:32986415
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