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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736447
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA5
Name: heat shock protein family A (Hsp70) member 5
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA5increases expressionEXP 6480464CTDArsenic results in increased expression of HSPA5 proteinPMID:19818359
HSPA5multiple interactionsEXP 6480464CTD[arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of HSPA5 mRNA; [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression of HSPA5 mRNAPMID:35809665
HSPA5affects expressionISOHspa5 (Mus musculus)6480464CTDArsenic affects the expression of HSPA5 mRNAPMID:36117518
HSPA5decreases expressionISOHspa5 (Mus musculus)6480464CTDArsenic results in decreased expression of HSPA5 proteinPMID:22552367
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