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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730892
Species: Homo sapiens
RGD Object: Gene
Symbol: NFKB1
Name: nuclear factor kappa B subunit 1
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NFKB1decreases expressionEXP 6480464CTDArsenic results in decreased expression of NFKB1 mRNAPMID:19945496
NFKB1multiple interactionsISONfkb1 (Rattus norvegicus)6480464CTD[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of NFKB1 mRNA; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of NFKB1 mRNA]; Succimer inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of NFKB1 mRNA]; zingerone inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of NFKB1 mRNA]PMID:32402895 PMID:36822304
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