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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61958
Species: Rattus norvegicus
RGD Object: Gene
Symbol: S1pr1
Name: sphingosine-1-phosphate receptor 1
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S1pr1affects expressionISOS1PR1 (Homo sapiens)6480464CTDArsenic affects the expression of S1PR1 proteinPMID:24675094
S1pr1increases methylationISOS1PR1 (Homo sapiens)6480464CTDArsenic results in increased methylation of S1PR1 promoterPMID:21291286
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