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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1623761
Species: Mus musculus
RGD Object: Gene
Symbol: Abcc4
Name: ATP-binding cassette, sub-family C member 4
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc4affects methylationISOABCC4 (Homo sapiens)6480464CTDArsenic affects the methylation of ABCC4 genePMID:25304211
Abcc4increases expressionISOABCC4 (Homo sapiens)6480464CTDArsenic results in increased expression of ABCC4 proteinPMID:25752797
Abcc4increases transportISOABCC4 (Homo sapiens)6480464CTDABCC4 protein results in increased transport of ArsenicPMID:25752797
Abcc4multiple interactionsISOABCC4 (Homo sapiens)6480464CTDoltipraz promotes the reaction [ABCC4 protein results in increased transport of Arsenic]PMID:25752797
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