Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352962
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP3A4
Name: cytochrome P450 family 3 subfamily A member 4
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP3A4decreases activityISOCyp3a2 (Rattus norvegicus)6480464CTDArsenic results in decreased activity of CYP3A4 proteinPMID:19932728
CYP3A4multiple interactionsISOCyp3a2 (Rattus norvegicus)6480464CTDArsenic inhibits the reaction [Acetaminophen results in increased activity of CYP3A4 protein]PMID:19932728
Go Back to source page   Continue to Ontology report