GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | H2AX | increases expression | EXP | | 6480464 | CTD | Arsenic results in increased expression of H2AX mRNA; Arsenic results in increased expression of H2AX protein | PMID:29161537 PMID:31822296 PMID:34998823 | H2AX | multiple interactions | EXP | | 6480464 | CTD | [UNG protein affects the susceptibility to Arsenic] which affects the expression of H2AX protein; APOBEC3B protein affects the reaction [[UNG protein affects the susceptibility to Arsenic] which affects the expression of H2AX protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone affects the reaction [Arsenic results in increased expression of H2AX protein]; FTO protein affects the reaction [Arsenic results in increased expression of H2AX protein]; NFATC3 protein inhibits the reaction [Arsenic results in increased expression of H2AX protein]; YTHDF2 protein affects the reaction [FTO protein affects the reaction [Arsenic results in increased expression of H2AX protein]] | PMID:31822296 PMID:34998823 | H2AX | increases expression | ISO | H2ax (Mus musculus) | 6480464 | CTD | Arsenic results in increased expression of H2AX protein | PMID:34998823 | H2AX | multiple interactions | ISO | H2ax (Rattus norvegicus) | 6480464 | CTD | [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Zinc deficiency] results in increased expression of H2AX protein | PMID:31542844 | |
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