Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344695
Species: Homo sapiens
RGD Object: Gene
Symbol: SOX2
Name: SRY-box transcription factor 2
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SOX2increases expressionEXP 6480464CTDArsenic results in increased expression of SOX2 mRNAPMID:29396848
SOX2multiple interactionsEXP 6480464CTD[Arsenic co-treated with Estradiol] results in decreased expression of SOX2 mRNA; [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SOX2 mRNAPMID:32525701 PMID:33047385
SOX2increases expressionISOSox2 (Mus musculus)6480464CTDArsenic results in increased expression of SOX2 mRNA; Arsenic results in increased expression of SOX2 proteinPMID:23221970 PMID:33124703
Go Back to source page   Continue to Ontology report