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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:27539
Term: isatin
Definition: An indoledione that is the 2,3-diketo derivative of indole.
Chemical ID: MESH:D007510
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsISORGD:7310026480464CTD[Copper binds to Isatin binds to 2-2-aminoethylpyridine] which results in increased cleavage of CASP3 protein [Copper binds to Isatin binds to trimethylenediamine] which results in increased cleavage of CASP3 protein

PMID:17327230
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