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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:27510
Term: umbelliferone
Definition: A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7.
Chemical ID: MESH:C031477
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxmultiple interactionsEXP 6480464CTD2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [7-hydroxycoumarin inhibits the reaction [Glycerol results in increased expression of BAX protein]]; 7-hydroxycoumarin inhibits the reaction [Glycerol results in increased expression of BAX protein]PMID:34409680
Baxincreases expressionISOBAX (Homo sapiens)6480464CTD7-hydroxycoumarin results in increased expression of BAX proteinPMID:15964220
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