GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MAPT | decreases expression | EXP | | 6480464 | CTD | Folic Acid results in decreased expression of MAPT mRNA | PMID:21867686 | MAPT | decreases expression | ISO | Mapt (Mus musculus) | 6480464 | CTD | Folic Acid results in decreased expression of MAPT mRNA | PMID:25629700 | MAPT | multiple interactions | ISO | Mapt (Mus musculus) | 6480464 | CTD | Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of BAD protein modified form]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of BCL2 protein]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of BCL2L1 protein]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of IGF1R protein modified form]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of SIRT1 protein]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in decreased expression of SOD2 protein]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CASP12 protein modified form]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CASP3 protein modified form]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CASP9 protein modified form]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CYCS protein]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of FADD protein]; Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of FAS protein]; Folic Acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein] | PMID:28422052 PMID:29068127 | | ||||||||||||||||||||||
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