GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | multiple interactions | EXP | | 6480464 | CTD | [Folic Acid co-treated with Isoflavones] results in decreased expression of BAX protein; [Vitamin E co-treated with Folic Acid] affects the expression of BAX protein; Folic Acid inhibits the reaction [Homocysteine results in increased expression of BAX mRNA]; Folic Acid inhibits the reaction [Nicotine results in increased expression of BAX protein] | PMID:16933212 PMID:20060418 PMID:29972271 PMID:31721048 | Bax | affects expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Folic Acid affects the expression of BAX mRNA | PMID:16361273 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Folic Acid results in increased expression of BAX protein | PMID:31593741 PMID:33404076 PMID:35191561 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | Nicorandil inhibits the reaction [Folic Acid results in increased expression of BAX protein]; nilotinib inhibits the reaction [Folic Acid results in increased expression of BAX protein]; PTHLH protein inhibits the reaction [Folic Acid results in increased expression of BAX protein]; Trimetazidine inhibits the reaction [Folic Acid results in increased expression of BAX protein] | PMID:16672315 PMID:31593741 PMID:33404076 PMID:35191561 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | Folic Acid affects the reaction [Homocysteine affects the expression of BAX mRNA]; Folic Acid affects the reaction [Homocysteine affects the expression of BAX protein]; Folic Acid inhibits the reaction [aluminum maltolate results in increased expression of BAX protein]; Folic Acid inhibits the reaction [Camptothecin results in decreased expression of BAX mRNA] | PMID:27113042 PMID:29250709 PMID:30581319 | |
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