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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550066
Species: Mus musculus
RGD Object: Gene
Symbol: Rfc1
Name: replication factor C (activator 1) 1
Acc ID: CHEBI:27470
Term: folic acid
Definition: An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation.
Chemical ID: MESH:D005492
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDRFC1 protein mutant form promotes the reaction [FOLR1 protein mutant form results in decreased abundance of Folic Acid]

PMID:18926688
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.