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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353911
Species: Homo sapiens
RGD Object: Gene
Symbol: OGG1
Name: 8-oxoguanine DNA glycosylase
Acc ID: CHEBI:27470
Term: folic acid
Definition: An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation.
Chemical ID: MESH:D005492
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
OGG1increases expressionEXP 6480464CTDFolic Acid results in increased expression of OGG1 mRNAPMID:36354958
OGG1multiple interactionsEXP 6480464CTDFolic Acid inhibits the reaction [Arsenic results in decreased expression of OGG1 mRNA]PMID:35490796
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