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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353608
Species: Homo sapiens
RGD Object: Gene
Symbol: MXD1
Name: MAX dimerization protein 1
Acc ID: CHEBI:27470
Term: folic acid
Definition: An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation.
Chemical ID: MESH:D005492
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MXD1multiple interactionsEXP 6480464CTD[Ethanol co-treated with Folic Acid] results in increased expression of MXD1 mRNA; [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of MXD1 mRNAPMID:23378141 PMID:24657277
MXD1decreases expressionISOMxd1 (Mus musculus)6480464CTDFolic Acid results in decreased expression of MXD1 mRNAPMID:25629700
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