GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Serpine1 | multiple interactions | EXP | | 6480464 | CTD | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SERPINE1 mRNA | PMID:20938992 | Serpine1 | increases expression | ISO | SERPINE1 (Homo sapiens) | 6480464 | CTD | Folic Acid results in increased expression of SERPINE1 mRNA | PMID:30116142 | Serpine1 | increases methylation | ISO | SERPINE1 (Homo sapiens) | 6480464 | CTD | Folic Acid results in increased methylation of SERPINE1 gene | PMID:30116142 | Serpine1 | multiple interactions | ISO | SERPINE1 (Homo sapiens) | 6480464 | CTD | [Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SERPINE1 mRNA; [Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased methylation of SERPINE1 gene; Folic Acid inhibits the reaction [Methotrexate results in increased expression of SERPINE1 mRNA] | PMID:30116142 PMID:31170432 | |
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