GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PARP1 | increases cleavage | EXP | | 6480464 | CTD | 1,4-naphthoquinone analog results in increased cleavage of PARP1 protein | PMID:30871965 | PARP1 | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in increased cleavage of PARP1 protein]; FR 180204 promotes the reaction [1,4-naphthoquinone analog results in increased cleavage of PARP1 protein]; GSK690693 promotes the reaction [1,4-naphthoquinone analog results in increased cleavage of PARP1 protein]; pyrazolanthrone inhibits the reaction [1,4-naphthoquinone analog results in increased cleavage of PARP1 protein]; SB 203580 inhibits the reaction [1,4-naphthoquinone analog results in increased cleavage of PARP1 protein] | PMID:30871965 | |
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