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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3015
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lox
Name: lysyl oxidase
Acc ID: CHEBI:27413
Term: beta-aminopropionitrile
Definition: An aminopropionitrile carrying an amino group at the beta-position.
Chemical ID: MESH:D000629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Loxdecreases activityEXP 6480464CTDAminopropionitrile results in decreased activity of LOX protein

PMID:19524603
Loxdecreases activityISORGD:7323436480464CTDAminopropionitrile results in decreased activity of LOX protein

PMID:22367676
Loxdecreases activityISORGD:7368466480464CTDAminopropionitrile results in decreased activity of LOX protein

PMID:16023247
Loxmultiple interactionsISORGD:7368466480464CTDAminopropionitrile inhibits the reaction [cupric chloride results in increased activity of LOX protein]

PMID:25044713
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.