GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IFNG | increases expression | ISO | Ifng (Mus musculus) | 39939037 | RGD | tetrachloromethane increases expression of Ifng protein in serum | | IFNG | decreases expression | ISO | Ifng (Rattus norvegicus) | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of IFNG protein | PMID:15603720 | IFNG | increases expression | ISO | Ifng (Rattus norvegicus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of IFNG mRNA; Carbon Tetrachloride results in increased expression of IFNG protein | PMID:15123359 PMID:18006644 PMID:23374533 | IFNG | increases expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of IFNG mRNA; Carbon Tetrachloride results in increased expression of IFNG protein | PMID:17038628 PMID:17133483 PMID:17412915 PMID:18279442 PMID:18395288 PMID:19913046 PMID:27477297 PMID:31697926 PMID:37573684 | IFNG | multiple interactions | ISO | Ifng (Rattus norvegicus) | 6480464 | CTD | [Melatonin co-treated with Folic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of IFNG mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of IFNG protein]; Folic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of IFNG mRNA]; IFNG protein inhibits the reaction [Carbon Tetrachloride results in increased expression of FN1 protein]; IFNG protein inhibits the reaction [Carbon Tetrachloride results in increased expression of HGF mRNA]; oxymatrine inhibits the reaction [Carbon Tetrachloride results in decreased expression of IFNG protein] | PMID:12445174 PMID:15030980 PMID:15603720 PMID:18006644 PMID:23374533 | IFNG | multiple interactions | ISO | Ifng (Mus musculus) | 6480464 | CTD | [Ethanol co-treated with Carbon Tetrachloride co-treated with 4-O-methylhonokiol] results in decreased expression of IFNG mRNA; alisol B 23-acetate inhibits the reaction [Carbon Tetrachloride results in increased expression of IFNG protein]; CD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of IFNG mRNA]; Colchicine inhibits the reaction [Carbon Tetrachloride results in increased expression of IFNG protein]; ginkgolide A affects the reaction [Carbon Tetrachloride results in increased expression of IFNG protein]; ginsan inhibits the reaction [Carbon Tetrachloride results in increased expression of IFNG mRNA]; NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of IFNG protein]]; PLAT protein affects the reaction [Carbon Tetrachloride results in increased expression of IFNG protein]; PLAU protein affects the reaction [Carbon Tetrachloride results in increased expression of IFNG protein]; PLAUR protein affects the reaction [Carbon Tetrachloride results in increased expression of IFNG protein]; tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of IFNG protein] | PMID:18279442 PMID:18395288 PMID:19913046 PMID:27477297 PMID:28689299 PMID:31697926 PMID:37573684 | | ||||||||||||||||||||||
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