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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736923
Species: Homo sapiens
RGD Object: Gene
Symbol: TBXAS1
Name: thromboxane A synthase 1
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TBXAS1affects expressionISOTbxas1 (Mus musculus)6480464CTDCarbon Tetrachloride affects the expression of TBXAS1 mRNAPMID:17484886
TBXAS1increases expressionISOTbxas1 (Rattus norvegicus)6480464CTDCarbon Tetrachloride results in increased expression of TBXAS1 proteinPMID:12629582
TBXAS1multiple interactionsISOTbxas1 (Rattus norvegicus)6480464CTD[Carbon Tetrachloride co-treated with Phenobarbital co-treated with Methoxamine] results in increased expression of TBXAS1 proteinPMID:12500202
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